Biological Basis of Alcohol-Induced Cancer by Vasilis Vasiliou, Samir Zakhari, Helmut K. Seitz, Jan B.

By Vasilis Vasiliou, Samir Zakhari, Helmut K. Seitz, Jan B. Hoek

In the new years, an important quantity of study has emerged connecting the hyperlink among alcohol and melanoma. the sector has speedily complicated, specially because the complicated connection among alcohol and melanoma has numerous exact sub parts which are being investigated. This complaints quantity will comprise chapters established upon the presentation of the 2d overseas convention on Alcohol and melanoma in Colorado, 2013. a number of the themes discover the impacts of alcohol on: liver and breast melanoma; telephone signaling and melanoma; stem cells; biomarkers and metabolomics; aerodigestive cancers; melanoma and the immune approach and more.

Show description

Read Online or Download Biological Basis of Alcohol-Induced Cancer PDF

Similar molecular biology books

Molecular Analysis and Genome Discovery

Molecular research and Genome Discovery, moment version is a totally revised and up to date new version of this winning booklet. The textual content offers a accomplished evaluate of contemporary advancements within the fast paced box of molecular established diagnostics of illness markers. Key innovations and purposes are supplied along sensible details on present concepts at present being researched and built.

Structural Aspects of Protein Synthesis

This hugely illustrated publication presents an updated description of the constitution and serve as of the interpretation method together with ribosomes, tRNAs, translation components, antibiotics and aminoacyl-tRNA synthetases. study on translation is present process swift alterations and is receiving major awareness as evidenced by means of the Nobel Prize in Chemistry 2009.

Stress Responses: Methods and Protocols

This quantity specializes in detecting diversified mobile stresses, measuring pathological results in the phone, and investigating the function of mobile stresses in choose ailments. moreover, this ebook stories the crosstalk among assorted rigidity pathways, tension responses in the course of aging, and concentrating on pressure for regenerative medication.

Regulation of Ca2+-ATPases,V-ATPases and F-ATPases

The organic membranes of mobile association enfold a massive staff of membrane proteins referred to as the ATPases, which aren't basically flexible in protecting chemical gradient and electric capability around the membrane but in addition deliver metabolites beneficial for phone metabolism and force out pollution, waste items and solutes that differently can shrink cellphone capabilities.

Extra info for Biological Basis of Alcohol-Induced Cancer

Sample text

9 drinks/day [108]. Chronic heavy alcohol consumption can cause relative folate deficiency due to the negative effects of alcohol on folate metabolism, including malabsorption, increased excretion, or enzymatic suppression. Based on the above interactions between folate and alcohol, it would be expected that high folate intake should ameliorate the association between alcohol intake and risk for breast cancer that is caused by this mechanism. Examination of epidemiological studies revealed inconsistencies in the findings.

The study reported that women who drank alcohol were “likely to be younger, leaner, more affluent, and to do strenuous exercise more frequently” and more likely to “have ever used oral contraceptives and to be currently using hormone replacement therapy” than nondrinkers. 29 for women who drank 3–6, 7–14, and 15 or more drinks/week, respectively. The study estimated a 12 % increase in breast cancer risk per 10 g increment of alcohol intake. 12. The Women’s Health Study in the USA conducted a 10-years follow-up on 38,454 women 45 years or older who were free of cancer and cardiovascular disease at baseline and provided detailed dietary information, including alcohol consumption [27].

Risk did not vary with alcohol type or by patterns of use (recent use, intake prior to age 20 years) [23]. 8. Information about alcohol intake was obtained using a questionnaire from women 40–75 years old who participated in a screening program in central Sweden [24]. Breast density is a risk factor for breast cancer. The impact of alcohol consumption on mammographic density was assessed for 1,207 cases from three populations (Japan, Hawaii, California) [25]; alcohol intake was estimated from “self-administered questionnaire” and recorded as “ever vs.

Download PDF sample

Rated 4.94 of 5 – based on 17 votes