Bovine Genomics by James Womack

By James Womack

The genetic info being unlocked through advances in genomic and excessive throughput applied sciences is swiftly revolutionizing our figuring out of developmental tactics in bovine species. this knowledge is permitting researchers unheard of perception into the genetic foundation of key features. Bovine Genomics is the 1st publication to compile and synthesize the knowledge realized in the course of the bovine genome sequencing undertaking and view its functional program to farm animals and dairy creation.

Bovine Genomics opens with foundational chapters at the domestication of livestock and conventional Mendelian genetics. construction on those chapters, assurance speedily strikes to quantitative genetics and the advances of complete genome applied sciences. major insurance is given to such issues as epigenetics, mapping quantitative path loci, genome-wide organization stories and genomic choice in farm animals breeding. The ebook is a useful synthesis of the sector written via a world crew of major researchers.

Providing wide-ranging assurance of the subject, Bovine Genomic, is a vital advisor to the sphere. the elemental and utilized technological know-how could be of use to researchers, breeders, and complex students.

Chapter 1 The Origins of livestock (pages 1–10): Matthew D. Teasdale and Daniel G. Bradley
Chapter 2 Mendelian Inheritance in livestock (pages 11–19): Frank W. Nicholas
Chapter three Genetics of Coat colour in farm animals (pages 20–33): Sheila M. Schmutz
Chapter four From Quantitative Genetics to Quantitative Genomics: a private Odyssey (pages 34–50): Morris Soller
Chapter five Cartography of the Bovine Genome (pages 51–62): James E. Womack
Chapter 6 background of Linkage Mapping the Bovine Genome (pages 63–74): Stephanie D. McKay and Robert D. Schnabel
Chapter 7 Bovine X and Y Chromosomes (pages 75–100): F. Abel Ponce de Leon and Wansheng Liu
Chapter eight livestock Comparative Genomics and Chromosomal Evolution (pages 101–108): Denis M. Larkin
Chapter nine Sequencing the Bovine Genome (pages 109–122): Kim C. Worley and Richard A. Gibbs
Chapter 10 Bovine Genome structure (pages 123–143): David L. Adelson
Chapter eleven Bovine Epigenetics and Epigenomics (pages 144–168): Xiuchun (cindy) Tian
Chapter 12 Mapping Quantitative Trait Loci (pages 169–191): Joel I. Weller
Chapter thirteen Genome?Wide organization reports and Linkage Disequilibrium in farm animals (pages 192–210): M. E. Goddard and B. J. Hayes
Chapter 14 Genomic choice in red meat farm animals (pages 211–233): Jeremy F. Taylor, Stephanie D. McKay, Megan M. Rolf, Holly R. Ramey, Jared E. Decker and Robert D. Schnabel
Chapter 15 effect of High?Throughput Genotyping and Sequencing at the identity of Genes and editions Underlying Phenotypic version in family livestock (pages 234–258): Michel Georges

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2009). Dr¨ ogem¨ uller et al. (2009, 2010) have mapped the belted pattern to a 336-kb region near the telomeric end of BTA3, using a genome scan. This region corresponds to a region on human chromosome 2 and mouse chromosome 1. The candidate gene in this region that appeared the most promising was a transcription factor, HES6 for hairy enhancer of split 6 from Drosophila. Although the complete coding sequence of HES6 was studied, and they identified ten polymorphisms, no polymorphism cosegregated with the belted pattern.

Journal of Heredity 90: 233–236. L. (2007). Genetic effects on coat colour in cattle, dilution of eumelanin and phaeomelanin pigments in an F2-Backcross Charolais×Holstein population. BMC Genetics 16: 56–67. F. (1996) Red coat color in Holstein cattle is associated with a deletion in the MSHR gene. Mammalian Genome 7: 317–318. , Howe, L. (2008) Coat-colour dilution and hypotrichosis in Hereford crossbred calves. New Zealand Veterinary Journal 56: 74–77. , Lien, S. (1995) The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination.

3). A limited number of Galloway cattle tested suggest that this same gene interaction will explain the solid coat colors in this breed. Although dun and silver dun are not uncommon in Galloway, any shade of red is rare. 3 MC1R. Coat colors in Highland cattle resulting from the genotype at both PMEL and PEML genotype +/+ +/del del/del MC1R genotype ED /-(any second allele) e/e or e/E+ or E+ /E+ Black Dun Silver dun Red (dark red) Yellow (light red) Cream P1: SFK/UKS BLBS104-03 P2: SFK Womack 28 February 27, 2012 9:41 Trim: 244mm×172mm Bovine Genomics Some diluted black cattle have been described to have a thinner coat than usual.

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