Breed Predispositions to Disease in Dogs and Cats by Alex Gough

By Alex Gough

Here's a finished connection with the entire illnesses and issues of canine and cats which are both inherited or extra normal in convinced breeds. there is not any different unmarried publication that covers this topic. info on breed-related illnesses from a number of top of the range assets are accrued jointly in a single position for the 1st time. while you are a veterinary physician or scholar wanting a convenient reference booklet, or a breeder desirous to recognize extra approximately your personal breed then this publication could be beneficial.

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24:1 • 50% bilateral • Age of onset usually 4 –7 months but can be older Carpal soft-tissue injury • Especially seen in working dogs Neurological conditions Congenital deafness • Signs seen from birth Cerebellar degeneration • Familial • Uncommon • Signs seen at 6–8 weeks Lysosomal storage disease – ceroid lipofuscinosis • Autosomal recessive inheritance • Rare • Signs seen at 1–2 years Ocular conditions Nodular episclerokeratitis • Breed predisposition • Usually presents at 2–5 years Chronic superficial keratitis (pannus) • Breed predisposition Primary lens luxation • Simple autosomal recessive inheritance suggested • Age of onset: 3–5 years • Often followed by glaucoma • Schedule 1 of the BVA/KC/ISDS Eye Scheme Border Terrier 29 Cataract BORZOI Eye Scheme Dermatological conditions Primary lymphoedema • No apparent sex predisposition • Usually occurs within first 12 weeks of life Collie eye anomaly • Congenital disorder, inheritance suspected • Low incidence in this breed • Schedule 1 of the BVA/KC/ISDS Eye Scheme Endocrine conditions Lymphocytic thyroiditis (causing hypothyroidism) • Reported to be inherited in one family of Borzois Generalised progressive retinal atrophy (GPRA) • Mode of inheritance unknown but presumed to be recessive • Clinically evident at 2 years of age Gastrointestinal conditions Gastric dilatation/volvulus • Possible breed predisposition Central progressive retinal atrophy (CPRA) or retinal pigment epithelial dystrophy (RPED) • Mode of inheritance unknown • Age of clinical onset: 1–2 years • More prevalent in the UK than in the USA.

Cases present, with haematuria and recurrent urinary tract infections more commonly than with uraemia, at 6 –15 months of age. Some cases present with cardiac disease. Hepatic cysts have not been seen in these cases Haematological conditions Pyruvate kinase deficiency • Inherited as an autosomal recessive trait Familial renal disease • Autosomal dominant inheritance • The condition is believed to be a glomerular basement-membrane disorder • Proteinuria may be an early indicator with cases progressing to renal failure at 1–8 years of age Musculoskeletal conditions Craniomandibular osteopathy • Aetiology unknown in this breed • Usually affects dogs aged 3–8 months CAIRN TERRIER Dermatological conditions Atopy • Common • May be more prevalent in females Endocrine conditions Diabetes mellitus • Possible breed predisposition • Usual age range: 4 –14 years; peak incidence: 7–9 years • Old, entire females are predisposed Gastrointestinal conditions Congenital bronchoesophageal fistula • Possible breed predisposition Congenital portosystemic shunt • Possible breed predisposition • Clinical signs usually seen in young dogs <1 year Microvascular portal dysplasia • Breed predisposition • Possibly inherited as a polygenic trait • May be asymptomatic Haemophilia B • Factor IX deficiency • Also known as Christmas disease • Inherited as a sex-linked trait • Less common than haemophilia A Inguinal hernia Neurological conditions Lysosomal storage disease – globoid cell leukodystrophy (Krabbe’s disease) • Autosomal recessive inheritance • Rare • Signs seen at 6–12 months Ocular conditions Refractory corneal ulceration • Breed predisposition • Usually middle-aged Ocular melanosis • Familial • Age of onset: 7–13 years • Predisposes to glaucoma • Schedule 3 of the BVA/KC/ISDS Eye Scheme Lens luxation • Autosomal dominant inheritance has been suggested • Age of onset: 4 –5 years Cataract • Inheritance suspected DOGS 43 Dogs 44 DOGS Retinal dysplasia • Mode of inheritance unknown, but autosomal recessive suspected Renal and urinary conditions Polycystic kidney disease • Autosomal recessive inheritance suggested • Cysts are found throughout the liver and kidneys from an early age (6 weeks).

Dogs 18 Basset hound thrombopathia • Inherited as an autosomal recessive trait • Aetiology unknown • May be a variant of Glanzmann’s thrombasthenia DOGS Tuberculosis under Infectious conditions Gastrointestinal conditions • See and Infectious conditions Mycobacterium avium • Rare condition • Possible breed predisposition Infectious skin diseases • See under Dermatological conditions Musculoskeletal conditions Temporomandibular dysplasia/luxation • Congenital dysplasia may predispose to luxation Ununited anconeal process • A true fracture of the process occurs in this breed Figure 1 Shampoos containing miconazole are useful for the treatment of Malassezia.

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