Brucella: Molecular and Cellular Biology by I. Lopez-Goni

By I. Lopez-Goni

The publication opens with chapters that target the improvement of molecular diagnostic instruments and those are through chapters on genetic evolution and its courting to pathogenicity. different issues comprise Brucella comparative genomics and proteomics, research of the constitution, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, methods to vaccine improvement, bacterium-host interactions, immune reaction, and masses extra. crucial analyzing for everybody with an curiosity in Brucella and brucellosis and advised interpreting for the broader physique of scientists with an curiosity in microbial diagnostics, microbial pathogenesis, mobile microbiology and immunology, and vaccine improvement.

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1998). A gene located downstream of p39 and identified as 39ugpa revealed, by the same technique, two hybridization patterns, one of them specific for B. , 1998). The Brucella gene coding for the cytoplasmic DnaK protein gave a DNA marker for B. , 1996a). DNA polymorphism of the bp26 gene, coding for a periplasmic protein of diagnostic importance, was assessed by nucleotide sequencing of the gene in reference strains of B. abortus, B. melitensis, B. suis, and B. , 2003). Only minor differences were found consisting of only one nucleotide substitution in B.

Taxonomy of the genus Brucella. Ann. Inst. Pasteur Microbiol. 138:235–238. , and Fernández-Lago, L. 2000. DNA polymorphism in the genus Brucella. Microbes Infect. 2:1089–1100. , and Dubray, G. 1996. Cloning, nucleotide sequence, and expression of the Brucella melitensis omp31 gene coding for an immunogenic major outer membrane protein. Infect. Immun. 3751. , and Fernández-Lago, L. 1999. Molecular characterization of a Brucella species large DNA fragment deleted in Brucella abortus strains: evidence for a locus involved in the synthesis of a polysaccharide.

Bacteriol. 95:444–448. B. 1968b. Homologies of deoxyribonucleic acids from Brucella ovis, canine abortion organisms, and other Brucella. J. Bacteriol. 96:1783–1790. S. 1997. The characterisation of Brucella strains isolated from marine mammals. Vet. Microbiol. 57:373–382. G. 1999. Genomic fingerprinting and development of a dendrogram for Brucella spp. isolated from seals, porpoises, and dolphins. J. Vet. Diagn. Invest. 11:152–157. , and Ramuz, M. 1998a. Differences in chromosome number and genome rearrangements in the genus Brucella.

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