Cancer Clinical Trials: Proactive Strategies (Cancer by Stanley P. L. Leong

By Stanley P. L. Leong

Scientific trials stay crucial car for bettering the care of melanoma sufferers. this article provides the basic elements and demanding situations concerning scientific investigations. prime specialists speak about the severe concerns protecting the spectrum of vital issues from making plans to program.

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Additional info for Cancer Clinical Trials: Proactive Strategies (Cancer Treatment and Research)

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In addition to clinical trials, CTEP manages programs for "compassionate" and expanded use. If a CTEP-sponsored investigational agent has been found to have reproducible clinical efficacy, such as objective responses in the setting of a phase 2 trial, CTEP may provide the agent for "compassionate" use under its Special Exception program. These are single-patient protocols for individuals with the appropriate cancer type who have no other treatment options and are not eligible for an appropriate clinical trial.

10. Shakespeare, W, Julius Caesar. Act 3, scene 2. Chapter 3 NCI'S CANCER THERAPY EVALUATION PROGRAM: A COMMITMENT TO TREATMENT TRIALS Jeffrey S. Abrams, MD, Anthony Murgo, MD, Michaele C. Christian, MD Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland, USA 1. ' The trials are coordinated or conducted by different Divisions/Programs within the NCI, including the Division of Cancer Treatment and Diagnosis (DCTD), the Division of Cancer Prevention, the Cancer Centers Program, the Specialized Programs of Research Excellence (SPORES) and the Center for Cancer Research.

In examining the validity of the informed consent process, the IRB will consider broadly two major factors: are the patients adequately informed about the study and is their choice fully voluntary. In addition to ensuring that the ICF is written in a level suitable for the reading level and education of the potential subjects, the IRB will check that all the requisite information discussed below is included in the ICF (and thus should be discussed in the process). To ensure that patients who enter the study do so voluntarily, the IRB will consider whether the study and the process of informed consent are designed to minimize potential coercive influences on the potential subjects.

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