Cellular Implications of Redox Signaling by Avihai Danon, Carlos Gitler

By Avihai Danon, Carlos Gitler

Redox rules, like phosphorylation, is a covalent regulatory procedure that controls a number of the general mobile capabilities of all residing cells and organisms. additionally, it controls how cells reply to rigidity regarding oxidants and unfastened radicals, which underlie many degenerative illnesses. This quarter is present process a transition from common wisdom to precise description of the elements and mechanisms concerned.

This beneficial publication offers a well timed uncomplicated description of a box whose relevance to telephone biology and degenerative ailments is of the maximum significance. It describes the cutting-edge, lays the rules for figuring out the reactions concerned, and offers the clients for destiny advancements. it may well function a easy textual content for any undergraduate or graduate direction that bargains with redox rules, oxidative rigidity and unfastened radicals less than general and pathological stipulations in bacterial, plant and animal cells.

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Res. Commun. , Schirmer, RH, Becker K. 1998. H u m a n placenta thioredoxin reductase: Isolation of the 42 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. Cellular Implications ofRedox Signalling selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds. /. Biol. Chetn. 273: 20096-20101 Hill KE, McCollum GW, Burk RF. 1997. Determination of thioredoxin reductase activity in rat liver supernatant. Anal. Biochem. 253: 123-125 Lee SR, Kim JR, Kwon KS, Yoon HW, Levine RL, Ginsburg A, Rhee SG.

Physiological functions of thioredoxin and thioredoxin reductase. Eur. J. Biochem. 267: 6102-6109 2. Holmgren A. 1985. Thioredoxin. Ann. Rev. Biochem. 54: 237-271 3. Nakamura H, Nakamura K, Yodoi J. 1997. Redox regulation of cellular activation. Ann. Rev. Immunol. 15: 351-369 4. Becker K, Gromer S, Schirmer RH, Miller S. 2000. Thioredoxin reduc­ tase as a pathophysiological factor and drug target. Eur. ]. Biochem. 267: 6118-6125 40 Cellular Implications ofRedox Signalling 5. Arner ESJ, Zhong L, Holmgren A.

1986. Immunohistochemical localization of thioredoxin thioredoxin reductase in mouse exocrine endocrine pancreas. Cell Tissue Res. 245:189-195 20. Hansson HA, Helander HF, Holmgren A, Rozell B. 1988. Thiore­ doxin, thioredoxin reductase show function-related changes in the gastric mucosa: Immunohistochemical evidence. Acta. Physiol. Scand. 132: 313-320 21. Tagaya Y, Maeda Y, Mitsui A, Kondo N, Matsui H, Hamuro J, Brown N, Arai KI, Yokota T, Wakasugi H, Yodi J. 1989. ATL-derived factor ADF—An IL-2 receptor/Tac inducer homologous to thioredoxin: Possible involvement of dithiol-reduction in the IL-2 receptor induc­ tion.

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