By Gretchen M. Lentz, Roger A. Lobo, David M. Gershenson, Vern L. Katz
Finished Gynecology provide you with whole, well timed, and simple entry to important details on the entire clinical and surgical matters affecting your perform. no matter if you're a resident or practioner, you'll get all of the sensible, in-depth insurance you want to remain on the leading edge of your box. Now in its 6th variation, this center reference, previously edited via Drs. Droegemueller, Stenchever, Mishell and Herbst, remains to be your fundamental source for in-depth and updated information.
not sleep thus far with the most recent gynecologic advances via transparent writing, a scientific concentration, and attention on evidence-based practices.
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seek the entire textual content on-line at www.expertconsult.com.
remain present on your box with the newest advances in breast care; endoscopy and hysteroscopy; menopausal bone future health; felony matters affecting our perform; and lots more and plenty more.
entry state of the art counsel at the most up-to-date purposes in diagnostic and interventional ultrasound - and lots of different crucial facets of today's perform - via certain sections at the molecular biology of particular gynecologic malignancies and a brand new bankruptcy on Fallopian Tube and first Peritoneal Cancer.
realize the interactions and affects of lady body structure on significant affliction strategies with a brand new bankruptcy at the interplay of scientific ailments and feminine Physiology.
deal with each patient's wishes with the Emotional concerns in Gynecology bankruptcy, now converted in partnership with a psychiatrist, and up to date info on depression/anxiety treatment.
Comprehensive Gynecology is the must-read textual content for either citizens and validated practitioners.
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Extra resources for Comprehensive Gynecology (6th Edition)
Most occur as the result of nondisjunction during meiosis or mitosis in which homologous chromosome pairs fail to disjoin. The result in meiosis is that one daughter cell receives two copies of the homologs and the other receives none. Fertilization with a gamete containing a normal chromosome complement will result in a zygote that is either trisomic or monosomic (Fig. 2-16). Molecular studies for the parent of origin have identified that the majority of autosomal aneuploidies result from nondisjunctional errors in maternal meiosis I.
2 Reproductive Genetics Interphase FISH 21 Y 13 18 X 21 13 18 Normal Normal male Trisomy 21 Trisomy 18 Figure 2-9 Interphase FISH on amniotic fluid cells to screen for aneuploidy. ) 24-color painting probes Figure 2-11 Example of spectral karyotyping (SKY) on standard metaphase chromosomes (Courtesy of Lisa Shaffer PhD, Washington State University). Deletion of 11p Figure 2-10 Example of FISH technology in the diagnosis of microdeletion syndromes. Here, standard karyotyping appears to be normal.
This fetus was diagnosed during a routine 20-week ultrasound for anatomy and growth and was found to have a large cystic hygroma and hydrops. The autopsy revealed a complex cardiac defect, abnormal kidneys, streaked ovaries, and malrotation of the gut with the appendix in the left lower quadrant. B, A 17-year-old woman with Turner syndrome. Note the short stature, poor sexual development, and increased carrying angles at elbows. Subject also has webbing of the neck. (A, Courtesy of Drs. W. ) carrier’s sex and nature of the translocation.